Importancia de la terapia de bacteriófagos en infecciones bacterianas multirresistentes
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https://doi.org/10.56048/MQR20225.9.2.2025.e579Palabras clave:
Bacteriófagos; infecciones multirresistentes; resistencia antimicrobiana, alternativa terapéutica, fagoterapiaResumen
El creciente peligro que representan las bacterias multirresistentes ha obstaculizado profundamente la efectividad de los antibióticos convencionales, subrayando la urgente necesidad de opciones terapéuticas alternativas. La terapia con fagos, definida por la aplicación de virus que atacan bacterias específicas, ha sido revitalizada como una estrategia de elección en este sentido. El objetivo de la investigación es examinar la importancia de la terapia de bacteriófagos como alternativa para el tratamiento de infecciones multirresistentes. Llevándose a cabo una revisión bibliográfica de la literatura sobre estudios clínicos y experimentales centrados en la eficacia de los bacteriófagos contra infecciones bacterianas multirresistentes. Los estudios revisados mostraron que la terapia con fagos es altamente específica en bacterias multirresistentes, a diferencia de las terapias tradicionales. Los estudios clínicos muestran un éxito terapéutico en las infecciones consideradas multirresistentes, particularmente en Pseudomonas aeruginosa, Klebsiella pneumoniae y Staphylococcus aureus (MRSA). El impacto de la terapia con bacteriófagos es un complemento frente a los antibióticos convencionales, por lo que, esta terapia debe ser considerada como una alternativa en el tratamiento de infecciones multirresistentes.
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